It is of great significance to improve working efficiency,reduce fatigue and illness by matching handle shape to user's hand.In order to meet user's comfort requirements and obtain a handle shape with a larger range of human body adaptation,a multi-sample reverse design method based on key points was proposed.By collecting the key points coordinate data for multiple target samples,the method takes the optimal percentile as the final data to model reconstruction,design and manufacture.Under the guidance of this method,taking the design of the operation handle of excavator as an example,multiple samples of oil sludge were obtained through man-machine experiments.A handle shape was generated by reverse design through optimized key point data,and the product was materialized by using rapid prototyping technology.Compared with single-sample reverse design,the multi-sample reverse design has results with wider range of human-machine applicability while satisfying comfort.