Introduction
Bimonthly, started in 1957
Administrator
Shanxi Provincial Education Department
Sponsor
Taiyuan University of Technology
Publisher
Ed. Office of Journal of TYUT
Editor-in-Chief
SUN Hongbin
ISSN: 1007-9432
CN: 14-1220/N
Administrator
Shanxi Provincial Education Department
Sponsor
Taiyuan University of Technology
Publisher
Ed. Office of Journal of TYUT
Editor-in-Chief
SUN Hongbin
ISSN: 1007-9432
CN: 14-1220/N
location: home > paper >
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Building and Analysis of Cell Impedance Response Model Based on Whole Cell RC Circuit
DOI:
10.16355/j.cnki.issn1007-9432tyut.2020.01.019
Received:
Accepted:
| Corresponding author | Institute | |
| WANG Kaiqun | College of Biomedical Engineering, Research Center for Nanobiomaterials & Regenerative Medicine, Taiyuan University of Technology |
abstract:
In this paper, the developed model, based on the principle of the entire cell RC circuit, was utilized to probe cell impedance response, so as to reveal the reason that the changes in electrical properties of intracellular components lead to alterations in overall impedance of the system. The results show that the impedance response of the system is highly influenced by alterations in cell membrane capacitance and resistance, cell-cell resistance, cell-electrode resistance. This study provides an in-depth theoretical basis for characterization of cell functions from the perspective of cell electrical properties, and provides an effective guidance to selecting appropriate frequency for impedance testing.
Keywords:
cellular electrical properties; whole cell RC circuit; impedance response; equivalent circuit model; frequency response;