The initial moisture state of urban underlying surface and low-impact development(LID) changes after different rainfall events. The effects of LID measures on the regulation and control of runoff is affected by the initial moisture state. To study the effects of different initial moisture content of soil and LID measures on runoff regulation, by taking Suining Sports Center as the research object, the Storm Water Management Model(SWMM) was built to simulate the runoff control and peak reduction effects of LID and traditional development mode under different initial moisture state with rainfall recurrence periods of 1, 2, 5, 10 and 20 a separately. The results show that: The runoff control rates of LID measures under natural, semi-saturated and saturated conditions are 36%-76.3%, 25.4%-56.8% and 16.9%-38.1% respectively. The peak flow rates are 10.1-208.4 L/s, 22.3-221.8 L/s and 39.2-240.7 L/s respectively. The runoff process in LID saturation state increases rapidly and peaks appear earlier. Compared with the traditional development mode in the same state, the reduction rates of runoff control are 6.5%-61%, 3.2%-50.8%, 2.1%-49.3%, and the peak reduction rates are 10.8%-57%, 5.4%-43.3% and 0.7%-36.9% respectively. Moreover, the effect of LID measures on Rainfall Runoff in low recurrence period is much greater than that in high recurrence period. It provides a theoretical basis of the design of urban low-impact development measures and the later operation management.