In order to increase the activity and stability of chilli peroxidase (CH-POD),some zinccontained effectors such as zinc acetate (ZA),zinc sulfate(ZS),zinc gluconate (ZG),and energy-contained effectors such as D-sorbitol (D-SOR),D-mannitol (D-MAN) were added in CH-POD extracted from chilli.The influence of effectors on activity was investigated and optimal effectors were selected,the effect of the effectors on Zeta potential of CH-POD was discussed also.The results show that,the above-mentioned effectors can raise the activity of CH-POD without exception,and the binary effector ZA-D-SOR (which is composed of ZA and D-SOR) is the best effector;addition of ZA-D-SOR can raise the thermal stability of CH-POD,lengthen its storage half-life,and increase the stability of its Zeta potential.