The CuO/ZnO precursors and catalysts with different Cu/Zn atomic ratios（nCu/nZn）were obtained by traditional co-precipitation method. The microscopic properties of precursors and catalysts were further characterized through XRD,FT-IR,AAS and H2-TPR,with emphasis on the effect of the nCu/nZn on phase transition of precursors and dispersion of the catalysts. The results show that different concentration of Cu2＋and Zn2＋in raw material results in the difference between impetus of isomorphous substitution reaction and the formation energy of phase, thus controlling the phase composition of the precursor. When nCu/nZn>75/25,the reactive impetus of the isomorphous substitution of Cu2＋in Cu2（CO3）（OH）2 compound by Zn2＋is greater than the formation energy of（Cu1-x,Znx）2（OH）2CO3phase,the precursors contain pure（Cu1-x,Znx）2（OH）2CO3phase;When nCu/nZn≤40/60,the reactive impetus of Zn2＋substitution by Cu2＋in the Zn5（CO3）2（OH）6 phase exceeds the formation energy of（Zn1-x,Cux）5（CO3）2（OH）6 phase, and the precursors of single（Zn1-x,Cux）5（CO3）2（OH）6 phase can be gained; When 40/60