On the basis of the health monitoring system of Taiyuan South Railway Station Steel Structure House, the measured acceleration data of the steel structure station during train arrival、departure and pass, crowd-induced excitations, and construction load excitation were analyzed, so as to evaluate the vibration response characteristics of steel structure station under different test conditions. The results show that the vertical acceleration response frequency of the structure is multiplied by train loading frequency. The response of the station under the excitation of train passing is significantly larger than that of train entering or leaving the station, and all of them will not cause significant vibration; 1 and 2 times frequency of crowd pace easily induce vertical vibration of the structure, but the Equivalent Sinusoidal Peak Acceleration(ESPA) peak of the structure does not exceed the code limit; the excitation frequency of construction load is above 10 Hz, which easily induce the vertical vibration of X-shaped steel column but the amplitude is relatively low; ESPA can better reflect the trend of acceleration amplitude. It is recommended to use this curve as a method to evaluate the comfort meas of large-span station house.