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Ma Xiaolu

Date:January 14, 2021Browse:Like:Source:

Dr.XiaoluMaisaprofessor at Department of Biomedical Engineering,Taiyuan University of Technology, Taiyuan 030024, PR China.

E-mail:maxiaolu@tyut.edu.cn

Education

2011-2017

University of Chinese Academy of Sciences, China

Biochemistry and Molecular Biology

Ph.D.

2007-2011

Northwest Agriculture & Forest University, China

Biotechnology

Bachelor

Professional Experience

2018-now

Taiyuan University of Technology, China

Research interests

- Genome instabilityand tumorchemo-resistance

-Mechanobiologyrelated to human diseases

Publications

>10articles

Selected publications

1.Ma X, Tang TS, Guo C.Regulation of translesion DNA synthesis in mammalian cells.Environ Mol Mutagen. 2020 Aug;61(7):680-692. doi: 10.1002/em.22359. Epub 2020 Feb 6. PMID: 31983077.(IF: 3.131)

2.MaX#, LiuH#, LiJ#, WangY, DingY, ShenH, YangY, SunC, HuangM, TuY, LiuY, ZhaoY, DongM, XuP, TangT*, GuoC*.“Polη O-GlcNAcylation governs genome integrity during translesion DNA synthesis”.Nature Communications 8,1941 (2017).doi:10.1038/s41467-017-02164-1.(IF: 12.123)

3.Zhu X#,Ma X#, TuY#, Huang M, Liu H, Wang F, Gong J, Wang J, Li X, Chen Q, Shen H, Zhu S, Wang Y, Liu Y, Guo C*, Tang T*.“Parkin regulates translesion DNA synthesis in response to UV radiation”.Oncotarget.2017 Apr05. doi: 10.18632/oncotarget.16855.(IF:5.168)

4.Wang K#,Ma X#, Zhang X, Wu D, Sun C, Sun Y, Lv X, Wu C*, Guo C*, Ruan J*. “Using ultra-sensitive next generation sequencing to dissect DNA damage-induced mutagenesis”.Scientific Reports, 2016 Apr 28;6:25310. doi: 10.1038/srep25310. (IF:4.269)

5.Gong J#, Huang M#, Wang F#,Ma X, Liu H, Tu Y, Xing L, Zhu X, Zheng H, Fang J, Li X, Wang Q, Wang J, Sun Z, Wang X, Wang Y, Guo C, Tang TS. “RBM45 competes with HDAC1 for binding to FUS in response to DNA damage”.Nucleic Acids Research, 2017 Nov 13.doi: 10.1093/nar/gkx1102.

6.TuY#, Liu H#, Zhu X#, Shen H,Ma X, Wang F, Huang M, Gong J, Li X, Wang Y, Guo C*, Tang TS*. “Ataxin-3 promotes genome integrity by stabilizingChk1”.Nucleic Acids Research, 2017 May 5;45(8):4532-4549.doi: 10.1093/nar/gkx095.

7.Liu H#, Li X#, Ning G#, Zhu S#,Ma X,Liu X, Liu C, Huang M, Schmitt I, Wüllner U, Niu Y, Guo C*, Wang Q*, Tang TS*. “The Machado-Joseph Disease Deubiquitinase Ataxin-3 Regulates the Stability and Apoptotic Function of p53”.PLOS Biology,2016 Nov 16;14(11):e2000733.

8.Liu Y,Ma X, Guo C*. “Effects of the N terminus of mouse DNA polymerase κ on the bypass of a guanine-benzo[a]pyrenyl adduct”.The Journal of Biochemistry, 2016 Apr;159(4):471-9. doi: 10.1093/jb/mvv118.

9.Wang Z, Huang M,Ma X, Li H, Tang T*, Guo C*. “REV1 promotes PCNA monoubiquitination through interacting with ubiquitinated RAD18”.Journal of Cell Science, 2016 Mar 15;129(6):1223-33.

10.Yang Y#, Liu Z#, Wang F#, Temviriyanukul P#,Ma X, Tu Y, Lv L, Lin YF, Huang M, Zhang T, Pei H, Chen BP, Jansen JG, de Wind N, Fischhaber PL, Friedberg EC, Tang TS*, Guo C. “FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress”.Nucleic Acids Research, 2015 Sep 30;43(17):8325-39.

Awards and Honors

Shanxi Provincial "Sanjin Talents” Support Program for Young Excellent Talents,2018

Projects

National Nature Science Foundation of Chinafor Youths( No. 31800684), 2019.01-2021.12.

Shanxi ProvinceNatural Science Foundationfor Youths(No.201801D221281),2018.12-2020.12.

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